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How Was Kinesin Discovered? [Solved]
The discovery of Kinesin-1 stemmed directly from real-time observation of fast axonal transport in isolated squid axoplasm by video-enhanced light microscopy. The non-hydrolyzable ATP analog, AMP-PNP, was found to inhibit fast axonal transport and to promote tight binding of organelles to microtubules.
Ron Vale (UCSF and HHMI): Discovering Kinesin
Vale explains how doing science often follows a winding path with unexpected, sometimes wonderful surprises, and uses his own …
The Workhorse of the Cell: Kinesin
Masterpieces of microengineering,
What is Kinesin? Ron Vale Explains
Ron Vale explains the inner workings of the motor protein called